Sistine Chapel in the Vatican (originally was a chapel in the Apostolic Palace) takes its name from Pope Sixtus IV, which was built in 1473-1481. Now the Chapel is a Museum and venue for the Papal Conclave where the Cardinals will choose a new Pope. Praise Chapel in her Painting her frescoes. ceiling is a famous cycle of frescoes by Michelangelo, created during 1508-1512, and considered one of the masterpieces of the art of the High Renaissance.